Age-trend analyses

The prevalences of asthma and hay fever were calculated in 1975, 1981, and 1990 after excluding those with missing data on the respective disease in each questionnaire. The European standard population was used to calculate age-standardized prevalences by 5-year age groups separately for men and women. 

Confidence intervals (CIs) were computed using an appropriate software. Separate incidences were computed among those reporting no asthma, hay fever, or chronic bronchitis in the 1975 questionnaire for the whole follow-up time (1976 to 1990) and for the first 6 years of follow-up (1976 to 1981). Cumulative incidences were calculated separately for men and women in age groups based on birth decade (1930 to 1939, 1940 to 1949, 1950 to 1957). 

Age-trend analyses were based on these three birth-decade groups and performed with the Rate Analysis program derived from the formulas given by Miettinen. Similarly incidence rate ratios (IRRs) by sex and their CIs were calculated by the Rate Analysis program. Basic statistics were derived by a software package. To compare incidences of asthma, hay fever, and chronic bronchitis during the first 6 and last 9 years of the follow-up time, incidences were calculated separately for two periods (1976 to 1981 and 1982 to 1990). 

The initial ages of subjects (ie, in 1975 and 1981) were used, and only those aged 25 to 44 years at the beginning of each follow-up were included in these analyses to make the age distributions of the two periods as comparable as possible. Person-years were calculated by multiplying the number of subjects at risk by the number of years (6 or 9) of follow-up. The European standard population was used to calculate age-standardized incidences per 10,000 person-years by 5-year age groups during 1976 to 1981 and 1982 to 1990, and CIs were computed by the Confidence Interval Analysis program. 

IRRs and their CIs were computed by stratifying 5-year age groups using the Rate Analysis program. To study the effects of hay fever and chronic bronchitis on the risk of developing asthma, the cumulative incidence of asthma during 1976 to 1990 was calculated among subjects reporting hay fever or chronic bronchitis in 1975, and among those not reporting it. IRRs were computed by stratifying birth decade using the Rate Analysis program.

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Viagra Australia: The diversity of Candida

The diversity of Candida species isolated was wide, and a high proportion of patients had more than one Candida species coexisting. CHROMagar performs as well as SABC to isolate Candida, but CHROMagar allows concurrent speciation, identifying 93% of species in this study compared with assimilation profiling. Although assimilation profiling is more accurate than CHROMagar identification, it is significantly more time consuming and expensive. The identification of germ tubes detected 84% of C albicans and C dubliniensis isolates. 

This method is rapid and inexpensive but only identifies these particular species. Very few sputum samples from the oral cavity grew Candida, suggesting that Candida grown from sputum samples represents true colonization of the bronchial tree. Fluconazole resistance was detected in one of 42 C albicans isolates and eight of 12 C glabrata isolates. This may be due to the frequent use of fluconazole in this group of patients receiving multiple courses of antibiotics for bacterial pulmonary exacerbations. 

Sensitivity of IgE detection by ImmunoCAP was less than standard SPTs, marginally for Aspergillus but markedly for Candida and Cladosporium. The cause for this is not known but has previously been reported in the literature. Alternative mechanisms of skin reactions, such as complement activation and IgG activation, do not explain the differences. It may be due to very low circulating levels of sIgE or differences in the allergen extract. ImmunoCAP has known advantages in terms of reproducibility, quantitation, and efficiency, making its use routine in many laboratories. 

However, if clinical allergy is suspected, SPTs should be used. The importance of sensitization has been debated in years past. One difficulty is that the definition of sensitization differs between studies, with variable sIgE cutoff levels being proposed. The present study defined patients with any rise in sIgE as sensitized and showed a greater FEV1 decline and increased pulmonary exacerbation rates for those sensitized to Aspergillus but not for those sensitized to Candida. 

However, it must be noted that this study was not powered to detect changes in lung function, and overall differences were small. The body of evidence appears to support reduced lung function with Aspergillus sensitization in both children and adults, with a suggestion that antifungal therapy may be beneficial. This is also true of patients who have asthma but do not have CF and has been linked to asthma control (severe asthma with fungal sensitization).

The clinical characteristics of our athletes population rule out the presence of an associated allergic asthma

Our results show increased inflammatory cells in the sputum of endurance athletes, when BHR athletes were compared with non-BHR athletes and control subjects. This does not exclude, however, the possibility that other mechanisms may also be involved but emphasizes the role of airway inflammation in BHR athletes. Both eosinophilic and neutrophilic patterns of bronchial inflammation have previously been reported in the sputum of endurance athletes. 

Increased total cell and lymphocyte counts in BAL fluid, and an infiltration by lymphocytes, eosinophils, and neutrophils of the submucosa have also been observed in specimens obtained from bronchial biopsies performed in cross-country skiers. Although an increased neutrophil count has been proposed as a specific feature of airway inflammation in endurance athletes, the BHR+ athletes in the present study showed an airway inflammation with increased eosinophil counts but normal neutrophil counts. 

Several factors may contribute to airway neutrophilia, such as prolonged and intense acute exercise or respiratory tract infection. The absence of respiratory tract infection at the time of the experiment, as well as the absence of undergoing an intense training session for at least 48 h before laboratory investigations, may explain the normal neutrophil counts in our study. Although normal exhaled NO levels have been occasionally reported in skiers with “ski asthma,” as in nonasthmatic runners, high exhaled NO concentrations were also observed in atopic skiers and atopic asthmatic subjects. 

The increased NO values observed in BHR+ athletes in the present study may be related to the more prevalent atopic status in this group. Hence, our results suggest that the airway inflammation profile in BHR+ athletes presents characteristics that are similar to those encountered in athletes with atopic asthma. However, the clinical characteristics of our athletes population rule out the presence of an associated allergic asthma.

Prevention: Music

While one has music in himself, he thinks right, because each right thought, each right feeling is a correct combination of tones.

There is music with not stave, but with six lines. Six cardinal lines and other subsidiary ones.

I talk a lot about music, but you say: “We are old, singing is for the young people." What is the song of the young people and what is the song of the old ones? Young people sing: “I got up.”, and the old ones sing: “I became bent", which means that they have become curvilinear with one more center, with a new center. One, who thinks in a musical way, bends his head, because it is heavy for him. He thinks: this is not arranged, that is not arranged; it hurts him here and there. If he sings to the ill place, because the thought is concentrated in that direction, more blood will come and soon he will recover. Without singing, the capillaries get narrower and the blood circulation does not happen in the right way.

People, who have tender feelings, have music. They may sing and play and stand high in respect to consciousness.

Tones are connected to the planets, to all heavenly bodies. The whole world is a musical composition. All planets have a special tone. All numberless worlds sing at various scales. Supreme beings and all higher hierarchies sing. You cannot be happy without music. You cannot understand Christianity without music. The first songs of the Christians were ordinary and sad, because they were chased and music was not so available. There are creatures in Nature, who does not allow singing. Bulgarians also think that it is not appropriate for an old man to sing.

All old mantras, from the hoary antiquity, are implemented in the songs, which I have given to you. If you sing them in the right way, you will benefit of them. These songs are created in accordance with laws of the future music. These are songs, which do not die. Do you think that they are being created today?

Sing a song to God. If you have made mistakes in singing, do not embarrass. When the song passes through the angles, they will correct it and when it reaches God, He corrects is so that it becomes the best symphony and then he returns it. When a brother or a sister comes and asks you to sing something, sing right away one song, two songs, as many as he wants. Never say that you will spoil your voice in this way. There shall be readiness in music, generosity. If you sing, you will gain. One, who sings, always gains. There is not a singer, who have sung and failed in the angels of music, but all that do not sing, have failed.

All tones are living beings in the Invisible world. “Do” is a specific tone only of certain rational beings. “Re" is a tone of other beings, etc. When we sing the scale, we are in connection to those beings. As long as we sing, they come and we exchange with them. The mind and the heart are the base of the laws of singing. We all, by working together, will achieve what God wants. Many creatures, by singing, by thinking, the thought goes rightly. It is a very hard work for a man to think by himself. While singing, think that you are being helped by the genes of music. The contemporary world may get rid of the sorrows only in this way. When people start singing, they will stop thinking ill.

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Viagra Australia: Treatment Diseases by Music

There are patients, who are treated by playing a violin, others - by playing a guitar, third ones - by playing a flute, etc. The various instruments have a specific impact on each person. If the patient likes to listen to a violin, you will play to him for a while, but with ascending vibrations, and not minor songs.

Tachycardia is treated by songs that start with the tone “do", not the one taken by a pitchfork, but the natural tone “do". If you take that tone correctly, you will immediately feel calmness in you, little joy as if you have gained something. No matter how little that joy is, it brings into your soul light, shining as if the Sun has risen. The basic tone “do" is the key to life. Everyone can do experiments in that direction, to verify that truth. When one wants to sing, first he must adjust himself to come upon the natural tone, the natural key. 

He will stand upright, remain calm for 10-15 minutes until he gets rid of all difficulties and contradictions that exist in his mind, will ponder over the reasonableness of life and then start singing. This means that this person is able to turn properly one of the musical keys given to him. That also means the sun to rise in him and the reasonable energy to start flowing in his organism. If the tone “do" is properly taken, one can take the life-giving energy in from the Sun and transmit it to all organs in his body.

If you have anemia, take frequently the tone “do". It is a tone of life. You will introduce a little gold in your organism through it.

One, who is a little stubborn, rough by nature, shall play Chopin. He will deliver mildness to him. One, who has lost the meaning of life, shall play Bach. One, who does not want to read and does not like to think, shall play Beethoven. One, who does not like poetry, shall play Mozart. Each musician is a good fruit and you will choose one or another according to your frame of mind. It is not one and the same whether you will eat apples, pears, cherries, grapes or another fruit.

The words “zum-mezum", in occult music, regulate. They are resultant forces that regulate everything. So when you want to tone yourself, you may sing the exercise “Power alive, spring, flowing".

At home, make a patient sing and he will recover. Make him sing “Sweetly, honeyed", then the other exercises. He can recover in this way.

While cooking, you shall sing. While digging a vineyard, you shall sing. While sowing and reaping the field, you shall sing. Singing is a formula. Singing is the right thought.

If you are ill, if you are hungry, sing the song “Goodness, goodness".

After each disturbance, a disease comes. When two people quarrel, cold or a wound, or infection comes. In that case, sing “Sweetly, honeyed". However, not all diseases can be treated by music.

If you are ill and poor, if you cannot see a doctor, and do not have money, sing a song like our song: “Life of our soul, which fills up the entire Earth, is beautiful". Sing it three times and you will recover. Then sing “In the beginning was the Word”. Is it real that I will recover once I sing it? Will you recover if you do not sing it? Sing it, do not hesitate. If you sing, you will recover.

In the future, doctors will treat by music and songs. You laugh at that, but people are unaware of how ridiculous and distorted they are without music. Music in relationships, in movements, in feelings, in thoughts, in deeds.

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